Investors

CTI BioPharma Annual Meeting of Shareholders

CTI BioPharma will hold its Annual Meeting of Shareholders on Friday, April 29, 2016, at 10 a.m. Pacific Daylight Time at CTI BioPharma’s corporate headquarters, 3101 Western Avenue, Seattle, WA 98121. Since this meeting is not a public assembly and in the direct interest of an orderly meeting, only CTI BioPharma shareholders of record as of February 26, 2016, or persons holding proxies from shareholders, and other persons invited to the meeting by the Board of Directors or management of the Company, shall be admitted to the meeting.

Management may require any person who is not a shareholder of record but claims to be a beneficial owner of stock of the Company to present evidence (either in the form of a proxy, written authorization or certification of participation) from the record holders (e.g., broker, bank or other nominee), indicating that such person is in fact a beneficial owner of stock of the Company to be submitted.

YOUR VOTE IS VERY IMPORTANT.

Whether or not you plan to attend the meeting, it is important that your shares be represented; therefore, we ask our Italian shareholders to print a proxy card and return it together with completed certification of participation (which can be obtained from your broker).

In the U.S., the Company follows the Securities and Exchange Commission (the “SEC”) rules that allow issuers to furnish proxy materials to their shareholders on the internet. If your shares are held in a U.S. bank or brokerage account, or if you are registered directly with the Company as the record holder of your shares, you may be eligible to vote your proxy electronically or by telephone.

For more information concerning the business to be conducted at the meeting, see the Company’s proxy statement and refer to your voting form for instructions.

ATTENDING THE MEETING

All CTI BioPharma shareholders are invited to attend the Annual Meeting. If you plan to attend, please contact Investor Relations at invest@ctibiopharma.com or call +1 206.272.4345 to R.S.V.P.